Analysis of polyadenylation factors interactions in human
Data were obtained from STRING database and EuPathDB Bioinformatics Resource Center with the corresponding human genome database. PPI network was visualized using the Cytoscape tool, principal proteins corresponding to polyadenylation factors were represented in the external network. Internal interactions represent proteins associate with polyadenylation process. (A) Emphasis into the central hub protein (CPSF 160). (B and C) Emphasis into the bottleneck proteins PPP1C and BRCA1. GO terms including Molecular functions and biological process were carried out using KEGG Pathways, STRING clusters, and Interior domains. Proteins were marked with the corresponding GO term color.