(A) Overlay of 8.4 Å in vitro monolayer map (EMD-10050) and resulting all-atom model of the E. coli core-singling unit (CSU) baseplate (PDB 6S1K), shown from the side (left) and the top as slices through the baseplate (right, top) and CheA.P4 domains (right, bottom). (B) Undipped (left) and dipped (right) conformations obtained from computational analysis of CheA.P4 conformational landscape. (C) Overlay of E. coli minicell map (EMD-10160) and resulting all-atom model, shown from the side (left) and the top as slices through the periplasmic domains (right, top) and baseplate (right, bottom). (D) All-atom model of the transmembrane chemosensory array, assembled from the CSU model in (C). In all panels, chemoreceptors are colored in red, CheA in blue, and CheW in gold. Panels (A) and (B) were adapted from [38] with permission; panel (C) was adapted from [33] with permission.