Overview of cryoET applications to chemosensory arrays.
(A) Schematics of the primary imaging contexts used to visualize chemosensory arrays. A range of vitrified sample thicknesses and attainable resolutions are given for each context. In general, as the thickness of a vitrified sample decreases, the attainable resolution increases, but often at the expense of fidelity to the native environment. (B) Renderings of representative core signaling unit (CSU) structures published in key studies and shown in chronological order from left to right. The EMDB accession code and associated imaging context are also indicated. Figure panels were kindly contributed by Dr. Alister Burt.