Figure 1
![(A) Chemical structure, volume, and pKa for Ser, Thr, and Tyr as well as for pSer, pThr, and pTyr. (B) Differences in backbone secondary chemical shift distributions between the phosphorylated and non-phosphorylated amino acids (left) and between the protonated and non-protonated phosphorylated states (right) measured in QQXQQ peptides [52].](https://port.silverchair-cdn.com/port/content_public/journal/essaysbiochem/66/7/10.1042_ebc20220060/1/ebc-2022-0060ci001.png?Expires=1717022933&Signature=cvttZs0C5Jcpu5PcFyPaFfpDa5nH73NOPQp0EIxPpNbx4ZmMVeWtWgu-jxLmI02-u8psQ5LNNwfmedgdZB7xutaYDGJ9hQ-x8Oetkxqhqa-9~1QgLcPuH9aq6r1ctKPHljfJatb~xAhsdM~KwwW8hWtVnSHsVB8dk7KfTepCZbkHCx5u8fNyFOtD1J8k5tdy6QmjcJoRyl4pXA2e54QEFXb2m8wZBF2s-uVyAsuyhUlSNDeGI-iBLYiZV-1JU0OKgsH6R7pbYUE2LJ2ArSuFZAuUM8~j7fOyycJ7uQYYUBYXWy7kkIkfyVQPyWr-yoBtk4BU75d5Pivp2mSZ9yQAog__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effects of phosphorylation of IDPs on chemistry
(A) Chemical structure, volume, and pKa for Ser, Thr, and Tyr as well as for pSer, pThr, and pTyr. (B) Differences in backbone secondary chemical shift distributions between the phosphorylated and non-phosphorylated amino acids (left) and between the protonated and non-protonated phosphorylated states (right) measured in QQXQQ peptides [52].