(A) The number of EBNA2 sequencing reads from immunoprecipitated Mutu III and GM12878 DNA are plotted per million background-subtracted total reads and aligned with the human genome at CD79A. The black arrow indicates the direction of gene transcription. GM12878 EBF-1 and H3K27 acetylation ChIP-seq data from ENCODE are also shown at the bottom of the panel. RBP-J binding sites identified by ChIP-seq [9] using the IB4 LCL are shown as their called MACS peaks (black bars) and summits of peaks (lines). (B) Transcription factor binding motifs at the upstream promoter-proximal peak at CD79A showing overlapping EBF-1 and potential RBP-J motifs. (C) EBF-1 and potential RBP-J overlapping motifs at the CD79A proximal promoter peak. (D) EBNA2 binding at CD79B. (E) Transcription factor binding motifs at the CD79B binding site.