(A) The expression levels of INK4 family in 374 HCC tissues and 50 normal liver tissues based on TCGA. (B) The expression levels of INK4 family in 50 HCC tissues and their paired adjacent normal liver tissues based on TCGA. (C) The ROC curve of INK4 family based on TCGA. (D–G) Quantitative PCR analysis of INK4 family members in clinical HCC samples. (H) Immunohistochemical-staining results of INK4 family members in clinical HCC samples. ***P<0.001.