Figure 7
Schematic diagram showing the characteristic domains including the key catalytic, pro, and other domains of human PCSK1 and PCSK2 enzymes
The domains are compared with the corresponding bacterial subtilisin and yeast (y) kexin enzymes (shown on the top panel). The key catalytic amino acid residues, D (Asp), H (His), S (Ser), and N (Asn) are depicted in the figure.