Throughout the course design features were used as learning activities to engage learners with the content. (A) A click-through image introducing the learner to new content step-by-step at the learner’s pace, e.g. the introduction of the bacterial CRISPR locus as shown here. (B) An interactive image to engage the learner with the content and introducing more detailed information at the learner’s pace, e.g. a hypothetical gene editing experiment as shown here. (C) Videos to break up content and to convey information in an easily comprehensible manner, e.g. on DNA cloning as shown here (D) Voluntary checks have been included at the end of each lesson to help the learner recapitulate the learned content, that amongst other contain multiple-choice questions as shown here.