FigureĀ 4.
(A) Domain overview of full-length A. thaliana CRY1 (top) and the synthetic CRY-microProtein that contains only the PH domain required for dimerisation. (B) The CRY-microProtein disrupts the formation of an active CRY homodimer by forming an inactive CRY-microProtein/CRY heterodimer, thereby sequestering the CRY monomers.
Synthetic microProteins can control cryptochrome function.

(A) Domain overview of full-length A. thaliana CRY1 (top) and the synthetic CRY-microProtein that contains only the PH domain required for dimerisation. (B) The CRY-microProtein disrupts the formation of an active CRY homodimer by forming an inactive CRY-microProtein/CRY heterodimer, thereby sequestering the CRY monomers.

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