Upper panel left (open bars). In subjects consuming a low-quality diet (n=204) that delivered the low amount of salt recommended by the U.K. and U.S.A. (∼5.8 g/day), increasing salt intake to 8.8 g/day for 4 weeks significantly increased systolic blood pressure (mean change of 2.7 mmHg with 95% CI, 0.3–5.0) [222]. Upper panel right (solid bars). In subjects consuming the DASH diet (n=208) that delivered the low amount of salt recommended by the U.K. and U.S.A. (∼5.8 g/day), increasing salt intake to 8.8 g/day for 4 weeks did not significantly increase systolic blood pressure (mean change of 1.6 mmHg with 95% CI, −0.7 to 3.8) [222]. Lower panel. Systolic blood pressure is significantly lower in subjects consuming the DASH diet (n=208) and a large amount of salt (8.8 g/day) for 4 weeks than in subjects consuming the low-quality diet (n=204) and a low amount of salt typically recommended by the U.K. and U.S.A. health authorities (5.8 g/day). Systolic blood pressure in subjects consuming the DASH diet and a large amount of salt (8.8 g/day) for 4 weeks is just as low as in subjects consuming the low-quality diet and an extremely low amount of dietary salt not recommended by the U.K. and U.S.A. health authorities (2.9 g/day). All of the graphs in these figures were drawn using DASH study data reported in [222]. The statistical analysis of the results in the upper panels is provided in [222]. The statistical analysis of the results in the lower panel is based on ANOVA with Holm-Sidak testing to adjust for multiple comparisons using data from reference [222].