Aortic wall thickness (A) and percentage of positive Masson’s Trichrome stain (B) were quantified as an indicator of aortic wall remodelling and collagen deposition, resepctively. Representative photographs of Masson’s Trichrome staining across all experimental groups, with scale bar representing 50 μM. Data expressed as mean ± SEM (n=6 mice per group) and analysed by two-way ANOVA with Tukey’s multiple comparisons; * indicates statistical significance P<0.05.