Superposition of HBGA binding pockets of GII.10 Vietnam (orange, pdb 3q38) GII.4 VA387 (gray, pdb 2obt) and GII.4 Saga P-dimers (blue, pdb 4 × 06) in complex with blood group B trisaccharide. Highly conserved amino acids in contact with l-fucose, the minimal binding motif, are highlighted (GII.4 Saga numbering).