Portland Press

Figure 2

Cells were treated with lobaplatin, hyperthermia and combination therapy (A). After treatment, cells were incubated in 5% CO2 at 37°C for 24 h. Cells were seeded in transwell without Matrigel. Twenty-four hours later, cells were photographed and counted (A–C). Cell invasion of 4T1 and MDA-MB-231 cells. Cells were treated as in (A), and in transwell with Matrigel (D). Twenty-four hours later, cells were photographed and counted in (E,F). (*P<0.05, **P<0.01, ***P<0.001 based on Student’s t test). Data are presented as the mean ± SD. Means and standard deviations in the bar charts are from three independent experiments.

Combination treatment suppressed the migration and invasion of breast cancer 4T1 and MDA-MB-231 cells

Cells were treated with lobaplatin, hyperthermia and combination therapy (A). After treatment, cells were incubated in 5% CO₂ at 37°C for 24 h. Cells were seeded in transwell without Matrigel. Twenty-four hours later, cells were photographed and counted (A–C). Cell invasion of 4T1 and MDA-MB-231 cells. Cells were treated as in (A), and in transwell with Matrigel (D). Twenty-four hours later, cells were photographed and counted in (E,F). (*P<0.05, **P<0.01, ***P<0.001 based on Student’s t test). Data are presented as the mean ± SD. Means and standard deviations in the bar charts are from three independent experiments.

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