Structure of human LDH-A with citrate bound at the allosteric site
The structure of human LDH-A containing four associated citrate molecules (file PDB 5w8i) is shown. (A) The enzyme and citrates are represented with orange lines and blue sticks, respectively. (B) The LDH-A subunits are rendered with cyan, magenta, orange, and blue ribbons, and citrates are depicted with green (carbon) and red (oxygen) spheres. The images were obtained with PyMol (The PyMol Molecular Graphics System, version 1.3, Schrödinger, LLC).