(A) The number of DEPs among A versus M, Q1 represents the A/M ratio < 0.667, Q2 represents the A/M ratio between 0.667 and 0.769, Q3 represents the A/M ratio between 1.3 and 1.5, Q4 represents the A/M ratio >1.5 (Q1 and Q2 are down-regulated proteins, and Q3 and Q4 are up-regulated proteins). (B) Volcano plot showing DEPs. The horizontal coordinate was the relative quantification of proteins after logarithmic transformation at the base of 2, and the vertical coordinate was the p-value of the test for the significance of differences after logarithmic transformation at the base of 10 (n=3 samples for each group).