GRP78 expression is high in MDA-MB-231R cells and anthracycline-resistant tumors
(A) Western blot showing that MDA-MB-231R cells expressed higher GRP78 levels than the parental MDA-MB-231 cells. (B) According to the TCGA database, breast cancer tissues express higher GRP78 levels than normal human breast tissue. (C and D) According to the TCGA (https://gepia.cancer-pku.cn/) and Oncomine (https://www.oncomine.org) databases, GRP78 expression levels were high in anthracycline-resistant cells, intermediate in cells with intermediate anthracycline sensitivity, and low in anthracycline-sensitive cells (C. Gyorffy Cell line, D. Schaefer sarcoma). *P<0.05; ***P<0.001.