Figure 3
(A) The translocation of P-p65 into nucleus induced by WISP1 was inhibited by treatment of NFκB inhibitor PTL, with the inhibition on the up-regulated expression of TNF-α. (B,C) PTL inhibited the LPS-induced nucleus translocation of P-p65 and the up-regulated expression of inflammation markers. (D) Results are expressed as the mean ± SEM relative gene expression, ***P<0.001,**P<0.01. n=3–5.
WISP1 regulates inflammation via the NF-κB signaling pathway in RAW macrophages

(A) The translocation of P-p65 into nucleus induced by WISP1 was inhibited by treatment of NFκB inhibitor PTL, with the inhibition on the up-regulated expression of TNF-α. (B,C) PTL inhibited the LPS-induced nucleus translocation of P-p65 and the up-regulated expression of inflammation markers. (D) Results are expressed as the mean ± SEM relative gene expression, ***P<0.001,**P<0.01. n=3–5.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept