Effect of age and exercise on hippocampal Bdnf mRNA expression (Mean ± SEM)
(A) Total Bdnf transcript expression in the hippocampus was significantly increased following 3 months of exercise compared with standard-housing in aged and young mice (*P<0.05 main effect of Treatment with post-hoc Tukey’s comparisons). (B) Bdnf exon 4 transcript expression in the hippocampus was significantly increased following 3 months of exercise compared with standard-housing in young and aged mice (*P<0.05 main effect of Treatment with post-hoc Tukey’s comparisons). n=3–4 per group.