Figure 3
(A) Systolic blood pressure (SBP) in the different weeks old PM2.5 offspring (one-way ANOVA with Tukey’s post hoc test, *P < 0.05 vs. control offspring, n = 8). (B and C) 24 h urine volume (B) and sodium excretion (C) in the 12-week-old PM2.5 offspring (B and C, two-tailed, unpaired t test, *P < 0.05 vs. control offspring, n = 8). (D) Renal histopathology was examined by H&E staining in the 12-week-old PM2.5 offspring; magnification 200×. Control offspring: offspring of vehicle-exposed paternal SD rats; PM2.5 offspring: offspring of PM2.5-exposed paternal rats.
Effects of paternal PM2.5 exposure on the regulation of blood pressure and renal functions in offspring

(A) Systolic blood pressure (SBP) in the different weeks old PM2.5 offspring (one-way ANOVA with Tukey’s post hoc test, *P < 0.05 vs. control offspring, n = 8). (B and C) 24 h urine volume (B) and sodium excretion (C) in the 12-week-old PM2.5 offspring (B and C, two-tailed, unpaired t test, *P < 0.05 vs. control offspring, n = 8). (D) Renal histopathology was examined by H&E staining in the 12-week-old PM2.5 offspring; magnification 200×. Control offspring: offspring of vehicle-exposed paternal SD rats; PM2.5 offspring: offspring of PM2.5-exposed paternal rats.

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