Figure 4.
(Α) Two sequential slices from a tomographic reconstruction of ivermectin-induced mitophagy are shown. Note that three phagophores are assembling on this mitochondrial fragment, and that the ER appears to occupy areas not covered by the phagophores. Colour scheme refers to this panel only. (B and C) During autophagy of Salmonella it is common to see multiple phagophores forming around bacterial clusters (B, bacteria are labelled with red asterisks and phagophores with yellow arrows) whereas the ER is frequently seen outlining the autophagosomal structures (C, ER labelled with blue arrows and bacteria with red asterisks). Mitophagy images shown in panel A are modified from ref. [71] whereas Salmonella images in B and C are modified from ref. [74].
Characteristics of mitochondrial and bacterial engulfment during autophagy.

(Α) Two sequential slices from a tomographic reconstruction of ivermectin-induced mitophagy are shown. Note that three phagophores are assembling on this mitochondrial fragment, and that the ER appears to occupy areas not covered by the phagophores. Colour scheme refers to this panel only. (B and C) During autophagy of Salmonella it is common to see multiple phagophores forming around bacterial clusters (B, bacteria are labelled with red asterisks and phagophores with yellow arrows) whereas the ER is frequently seen outlining the autophagosomal structures (C, ER labelled with blue arrows and bacteria with red asterisks). Mitophagy images shown in panel A are modified from ref. [71] whereas Salmonella images in B and C are modified from ref. [74].

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