(A) Dose-dependent cytotoxicity of the two compounds, as determined by MTT assay is shown. (B) TMPRSS2 and ACE2 mRNA expressions in control and treated (non-toxic dose of Mortaparib and Mortaparib^Plus) cells. (C) Immunostaining and (D) Western blotting showing the expression of TMPRSS2 and ACE2 in control and treated cells. Data were normalized against control and plotted as fold difference. Each data set represented the mean SD of at least three independent experiments. Statistical significance was defined as non-significant (nsp-value > 0.05), significant (*P-value ≤ 0.05), highly significant (***P-value ≤ 0.001) and extremely significant (****P-value ≤ 0.0001)