Figure 3
![(A) Interactions of the amino acid residues with the substrate 2-oxoglutarate (labelled as AKG383) and other amino acid residues around the active site of the HCS from Thermus thermophilus [9] complexed with alpha-ketoglutarate (PDB ID: 2ZTJ). (B) 3D format of the substrate 2-oxoglutarate. The bonds are represented by different colours: hydrogen bonds (blue), hydrophobic contacts (grey), Pi interactions (orange) and metal interactions (purple), respectively.](https://port.silverchair-cdn.com/port/content_public/journal/bioscirep/41/10/10.1042_bsr20211634/1/bsr-2021-1634ci003.png?Expires=1716888909&Signature=3e~EnhXW2Mrq~NjXL-YU1DDfdRq-LQXl3EZVLFjnDRRALqNOVmdHQuGY1YykfsdZaV0EjEtMc3uZhi2GC0HKgHu8GI6k466yKvBBg-T7pwyH3JsUM6JzeLvBgZs-dU860eqFTr7u9K1tgSp-03IIIrsgR0WSf4JWvEZ-55wjuY6jMtgK06yhL4pF4K9o5-5GhAVN1pNTzGwdnWwqg000y5cBsL~KfpoIb7OOipmgjqVuM57WfOHREnndt57NysiYOh2zCZxLa3NDsk0K8iovniw3L0bUrBe7YQVQrCiDv-CZVLzjobuHY9ZO8YKSCqxiC6W-We3rwABwfJUCsInpOg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Interactions of amino acid residues with the substrate of HCS from Thermus thermophilus
(A) Interactions of the amino acid residues with the substrate 2-oxoglutarate (labelled as AKG383) and other amino acid residues around the active site of the HCS from Thermus thermophilus [9] complexed with alpha-ketoglutarate (PDB ID: 2ZTJ). (B) 3D format of the substrate 2-oxoglutarate. The bonds are represented by different colours: hydrogen bonds (blue), hydrophobic contacts (grey), Pi interactions (orange) and metal interactions (purple), respectively.