(A) RBP binding sites tend to be more single-stranded. (B) m⁶A association is likely to alter RNA structure into more single-strandedness. Red circles represent m⁶A modifications. (C) mRNAs containing a tRNA-derived structural motif can be transported intercellularly more efficiently. (D) SHR RNA contained a strongly folded RG4 structure which was shown to trigger RNA-driven phase separation in endodermis cells.