Figure 1.
![Data for each of the 17 human PARP genes was downloaded from the Interferome 2.0 database [13], which contains manually curated microarray datasets of type I, II or III IFN-induced genes. Each dot represents an entry in which a given PARP gene was found to be significantly up-regulated (P < 0.05) within 24 h of IFN treatment in human cells, irrespective of the treatment time, cell type or type of IFN used. Datapoints in which PARP gene expression was not significantly changed or down-regulated relative to baseline are omitted for clarity. Multiple data points from the same dataset are often present.](https://port.silverchair-cdn.com/port/content_public/journal/biochemsoctrans/49/4/10.1042_bst20201212/1/bst-2020-1212c.01.png?Expires=1717077089&Signature=Ka~NSjJY3oju4ZD3uWMrBd1J2V~TpnFRcZ42mrvM2wQFVqwh4aE0bzvJv4JuFmNwqmc53APuu5RdEmenp57T3l-TEjWm-QeptDiRwgmteLVLKQ6o5p5XpRZAqqJ1btxlzEGhddKVvPWKhxhbfHmU0d87YEDkmsxR02VjkC-4HyXoqRaTMHC6883HbDcLxJ02dJqOYZRGb~yGkorbWGfQMnPDNGJbZWdoOQ0GwZVydxVrKeqPKBLYOQ-GBPR41Hrsspm28OZTnkbMLsXarsuDO8QR~yF1wslnouq~207UzzehnEljtXrEi5GnO7fgn4xfQWv5V0fGw9oPsIulBGT4fA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
IFN-induced gene expression changes of PARP family members.
Data for each of the 17 human PARP genes was downloaded from the Interferome 2.0 database [13], which contains manually curated microarray datasets of type I, II or III IFN-induced genes. Each dot represents an entry in which a given PARP gene was found to be significantly up-regulated (P < 0.05) within 24 h of IFN treatment in human cells, irrespective of the treatment time, cell type or type of IFN used. Datapoints in which PARP gene expression was not significantly changed or down-regulated relative to baseline are omitted for clarity. Multiple data points from the same dataset are often present.