Computational docking analysis of TMJ-12 with the PTEN protein
(A,B) The binding conformation of TMJ-12 in the active side of PTEN and the Schematic diagram representing the PTEN-binding site and proximate affinity of TMJ-12. (C,D) The binding conformation of Otoxin B in the active side of PTEN and Schematic diagram representing the PTEN-binding site and proximate affinity of Oxtoxin B. Black dots: carbon atoms; blue dots: nitrogen atoms; red dots: oxygen atoms; green dotted lines: hydrogen bonds; red combs: amino acid residues.