Figure 5
(A) Cancer-free survival curves of BM recipient mice which received BM from control (blue; n=30) and THS (green; n=32)-exposed donor mice. P-value was obtained by Log-Rank Mantel–Cox test. (B) Cumulative incidence functions for competing risk of solid tumor development (dashed lines; n=5 for control, n=9 for THS) with leukemia/lymphoma (solid lines; n=24 for control, n=17 for THS) as first observed event (control mice indicated in blue and THS mice in green). Competing risk analysis: Control vs. THS P=0.02 for leukemia/lymphoma, P=0.13 for solid tumors. (C) Correlation between the percentage of transplanted B cells and tumor latency of non-leukemia/lymphoma cancers in the combined control and THS cohorts. Control mice indicated in blue and THS mice in green. P-value was obtained using Spearman correlation.
THS exposure significantly affects leukemia and lymphoma development

(A) Cancer-free survival curves of BM recipient mice which received BM from control (blue; n=30) and THS (green; n=32)-exposed donor mice. P-value was obtained by Log-Rank Mantel–Cox test. (B) Cumulative incidence functions for competing risk of solid tumor development (dashed lines; n=5 for control, n=9 for THS) with leukemia/lymphoma (solid lines; n=24 for control, n=17 for THS) as first observed event (control mice indicated in blue and THS mice in green). Competing risk analysis: Control vs. THS P=0.02 for leukemia/lymphoma, P=0.13 for solid tumors. (C) Correlation between the percentage of transplanted B cells and tumor latency of non-leukemia/lymphoma cancers in the combined control and THS cohorts. Control mice indicated in blue and THS mice in green. P-value was obtained using Spearman correlation.

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