(A) Single video frames of a Ddhd1(+/−) and Ddhd1(−/−) mice walking on the bridge are shown as examples. FBA at toe-off position is indicated by white lines. (B) The FBA of mice at the 14 months of age. There were no significant differences between genotypes (n=3). (C) The FBA of mice at 24 months of age. Ddhd1(−/−) (n=3) showed a significant decrease in FBA compared with Ddhd1(+/−) (n=2). Same animals at different ages were used except one mouse of Ddhd1(+/−) which died after the examination at 14 months of age. Error bars represent the mean ± SD. For Ddhd1(+/−) versus Ddhd1(−/−), *: P=5.0 × 10⁻³ N.S., not significant. All data were analyzed using a two-tailed Student’s t test.