Figure 5
(A) The expression of ICAM-1 in HG-stimulated HGMCs was determined by quantitative reverse-transcription PCR (qRT-PCR); ***P<0.001 vs. the normal glucose (NG) group. (B) The protein level of ICAM-1 was measured by Western blot assay. (C) The viability of HG-stimulated HGMCs was measured by MTT assay. (D) The levels of IL-1β, IL-6 and TNF-α in HG-stimulated HGMCs were measured by ELISA; ***P<0.001 vs. the miR-negative control (NC) group; ### P<0.001 vs. the miR-141 mimics group.
MicroRNA (MiR)-141 diminishes the levels of inflammatory factors in high-glucose (HG)-induced human glomerular mesangial cells (HGMCs) through regulating intercellular adhesion molecule-1 (ICAM-1)

(A) The expression of ICAM-1 in HG-stimulated HGMCs was determined by quantitative reverse-transcription PCR (qRT-PCR); ***P<0.001 vs. the normal glucose (NG) group. (B) The protein level of ICAM-1 was measured by Western blot assay. (C) The viability of HG-stimulated HGMCs was measured by MTT assay. (D) The levels of IL-1β, IL-6 and TNF-α in HG-stimulated HGMCs were measured by ELISA; ***P<0.001 vs. the miR-negative control (NC) group; ### P<0.001 vs. the miR-141 mimics group.

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