Figure 3
(A) The expression of miR-141 in HG-stimulated HGMCs was determined by quantitative reverse-transcription PCR (qRT-PCR); ***P<0.001 vs. the normal glucose (NG) group. (B) The expression of SNHG15 after transfection of miR-141 mimics/negative control (NC) or miR-141 inhibitor/inhibitor NC into HG-stimulated HGMCs was detected by qRT-PCR. (C) The viability of HG-stimulated HGMCs was measured by MTT assay. (D) The levels of IL-1β, IL-6 and TNF-α in HG-stimulated HGMCs were measured by ELISA. ***P<0.001 vs. the miR-NC group; ### P<0.001 vs. the inhibitor NC group.
Overexpression of microRNA (miR)-141 declines the levels of inflammatory factors in high-glucose (HG)-induced human glomerular mesangial cells (HGMCs)

(A) The expression of miR-141 in HG-stimulated HGMCs was determined by quantitative reverse-transcription PCR (qRT-PCR); ***P<0.001 vs. the normal glucose (NG) group. (B) The expression of SNHG15 after transfection of miR-141 mimics/negative control (NC) or miR-141 inhibitor/inhibitor NC into HG-stimulated HGMCs was detected by qRT-PCR. (C) The viability of HG-stimulated HGMCs was measured by MTT assay. (D) The levels of IL-1β, IL-6 and TNF-α in HG-stimulated HGMCs were measured by ELISA. ***P<0.001 vs. the miR-NC group; ### P<0.001 vs. the inhibitor NC group.

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