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Figure 1

$(A) Representative micro-CT fault images of the murine tibia (scale bar = 1 mm). (B) Hematoxylin and eosin staining (scale bar = 100 μm). (C) Bone volume. (D) Bone volume fraction. (E) Bone surface/volume ratio. (F) Trabecular thickness. (G) Trabecular number. (H) Trabecular separation. Low-SR means 625 mg/kg/day and High-SR means 1800 mg/kg/day (*P<0.05 and **P<0.01).$

Effect of strontium ranelate on periprosthetic osteolysis in mice

(A) Representative micro-CT fault images of the murine tibia (scale bar = 1 mm). (B) Hematoxylin and eosin staining (scale bar = 100 μm). (C) Bone volume. (D) Bone volume fraction. (E) Bone surface/volume ratio. (F) Trabecular thickness. (G) Trabecular number. (H) Trabecular separation. Low-SR means 625 mg/kg/day and High-SR means 1800 mg/kg/day (*P<0.05 and **P<0.01).

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