Figure 4
(A) Omeprazole treatment enhanced the p-S6 (Ser235/236) and p-4EBP1 (Ser37/46) when compared with PBS-treated cells in both AGS and HGC-27 cells. (B) FTO knockdown resulted in the p-S6 (Ser235/236) and p-4EBP1 (Ser37/46) promoted. In the other hand, p-S6 (Ser235/236) and p-4EBP1 (Ser37/46) attenuate when FTO was overexpressed when compared with PBS-treated cells in AGS and HGC-27 cells different cell models.
FTO / mTORC1 signal axis played roles in omeprazole induced autophagy mediation

(A) Omeprazole treatment enhanced the p-S6 (Ser235/236) and p-4EBP1 (Ser37/46) when compared with PBS-treated cells in both AGS and HGC-27 cells. (B) FTO knockdown resulted in the p-S6 (Ser235/236) and p-4EBP1 (Ser37/46) promoted. In the other hand, p-S6 (Ser235/236) and p-4EBP1 (Ser37/46) attenuate when FTO was overexpressed when compared with PBS-treated cells in AGS and HGC-27 cells different cell models.

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