(A) Western blotting analysis on CXCL5 or CXCR2 expression following shRNA-mediated knockdown in Penl1 and Penl2 cells. (B) Depletion of CXCL5 or CXCR2 expression suppressed cell growth of PC cells. (C) Knockdown of CXCL5 or CXCR2 reduced BrdU incorporation in PC cell lines. The BrdU incorporation in Scr control was regards as 100%; n=3, *P<0.05. (D) Knockdown of CXCL5 induced caspase-3 activity in Penl1 and Penl2 cells. The caspase-3 activity in Scr control was regards as 100%; n=3, *P<0.05. (E) Depletion of CXCL5 expression reduced clonogenesis of PC cells. The colony formed in Scr control was regards as 100%; n=3, *P<0.05.