Acute effects of hot water extract of four most potent plants (A and C) A. latifolia, A. marmelos, T. foenum graecum, M. indica and (B and D) DPP-IV inhibitors: sitagliptin and vidagliptin on (A and B) glucose tolerance and (C and D) plasma insulin in high-fat fed rats expressed as line graphs and area under the curve
Blood glucose and plasma insulin were measured prior to and after oral administration of glucose alone (18 mmol/kg body weight, control) or in combination with plant extract (250 mg/5 ml/kg body weight,), Sitagliptin or Vidagliptin (both at 10 μmol/5 ml/kg, body weight). Values are mean ± SEM with n=6, *P<0.05, **P<0.01 and ***P<0.001, compared with lean rats and ΔP<0.05, ΔΔP<0.01 and ΔΔΔP<0.001 compared with high-fat fed controls.