Figure 10
The expression levels of COL1A1 showed a significant positive correlation with macrophages and CD4 + T cells, and it was a definite negative correlation with B cells. THBS2 was highly correlated with macrophages and dendritic cells. SPP1 showed the most significant negative correlation with B cells, and no correlation with CD8 + T cells. With the exception of CD4 + T cells, SPP1 showed a certain degree of positive correlation with the remaining immune infiltrating cells.
Correlation analysis between immune infiltrates and expression of COL1A1, THBS2, and SPP1 genes

The expression levels of COL1A1 showed a significant positive correlation with macrophages and CD4 + T cells, and it was a definite negative correlation with B cells. THBS2 was highly correlated with macrophages and dendritic cells. SPP1 showed the most significant negative correlation with B cells, and no correlation with CD8 + T cells. With the exception of CD4 + T cells, SPP1 showed a certain degree of positive correlation with the remaining immune infiltrating cells.

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