Figure 3
(A) Representative centred trajectory plots illustrate the trajectory paths of multiple human MSCs, SAOS2 and MG63 cells over 120 h of treatment in control (top panels) and V-BAP High [1 mM BEZ, 10 μM MPA, 0.6 mM VPA] (bottom panels) treatment conditions. (B) The trajectory lengths (left graph) and migratory speeds (right graph) of human MSCs (green), SAOS2 (orange) and MG63 (red) cells in control versus V-BAP Low [0.5 mM BEZ, 5 μM MPA, 0.6 mM VPA] and V-BAP High [1 mM BEZ, 10 μM MPA, 0.6 mM VPA] treated cultures. Data shown as means ± SEM (n=3 independent experiments), *P<0.05, **P<0.01.
V-BAP treatment inhibited cell migration

(A) Representative centred trajectory plots illustrate the trajectory paths of multiple human MSCs, SAOS2 and MG63 cells over 120 h of treatment in control (top panels) and V-BAP High [1 mM BEZ, 10 μM MPA, 0.6 mM VPA] (bottom panels) treatment conditions. (B) The trajectory lengths (left graph) and migratory speeds (right graph) of human MSCs (green), SAOS2 (orange) and MG63 (red) cells in control versus V-BAP Low [0.5 mM BEZ, 5 μM MPA, 0.6 mM VPA] and V-BAP High [1 mM BEZ, 10 μM MPA, 0.6 mM VPA] treated cultures. Data shown as means ± SEM (n=3 independent experiments), *P<0.05, **P<0.01.

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