Figure 2
ICA regulated the expression of ECM associated proteins in ADTC5 chondrocytes measured by qRT-PCR
(A–C) ICA eliminated the down-regulation of TNF-α on the expressions of SOX9 (A), AGG (B) and Col2α (C). (D and E) ICA eliminated the up-regulation of TNF-α on the expressions of MMP9 (D) and ADAMTS5 (E). Cells were treated with TNF-α (20 ng/ml) or TNF-α and ICA (10−6 mol/l) for 24 h. *P<0.05 and **P<0.01 were regarded as significance and extremely significance, respectively.