Effect of ebselen and vehicle treatment on colon length (A), number of faecal pellets (B), small intestinal length (C) and caecal weight (D). Treatment with vehicle or ebselen did not reverse reduced colonic length caused by CS, but ebselen treatment reduced colon length in the sham group (A). Both Ebselen and vehicle treatment did not rescue increased faecal pellet numbers due to CS (B). Caecal weight was unaffected due to vehicle or ebselen treatment (D; **P<0.01, ****P<0.0001).