Compared with cervical cancer without lymph node metastasis, LINC00636 was significantly up-regulated in solid cancer cells (A) and serum (B) (n=15). (C) The results of TCGA database also showed that the expression of LINC00636 in tumor cells with metastasis was significantly higher than that in patients without metastasis and (D) LINC00636 overexpression have poor prognosis for cervical cancer patients by Kaplan–Meier analysis. (E) Relative expression LINC00636 in various common tumor cell lines. (F) Twenty genes with the most significant difference were identified from three pairs of metastatic and non-metastatic cervical cancer patients by RNA-sequence analysis. Values were presented as means ± standard deviations of three independent experiments unless indicated. *: P<0.05, ***: P<0.001. Independent t test.