Figure 5
(A) The knockdown of Nrf2 was examined using Western blot analysis after transfection with si1/2-Nrf2. (B) Cell viability was assessed using CCK-8 assay. (C) Level of ROS in ARPE-19 cells. (D) Caspase-3 activity in ARPE-19 cells. n=3. *P<0.05 vs. control group; #P<0.05 vs. H2O2 group; &P<0.05 vs. H2O2+MADE group.
Effect of Nrf2 silencing on the protective effects of MADE on ARPE-19 cells

(A) The knockdown of Nrf2 was examined using Western blot analysis after transfection with si1/2-Nrf2. (B) Cell viability was assessed using CCK-8 assay. (C) Level of ROS in ARPE-19 cells. (D) Caspase-3 activity in ARPE-19 cells. n=3. *P<0.05 vs. control group; #P<0.05 vs. H2O2 group; &P<0.05 vs. H2O2+MADE group.

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