(A) The interactions between the miR614 and ZEB1, the miR-614 and MDM2 in both the SKOV3 (left panel) and A2780 (right panel) cells were detected by RNA-immunoprecipitation assay. (B) The mRNA expression levels of zeb1 and mdm2 in the SKOV3 and A2780 cells after ciRS-7 knockdown (si-ciRS-7) with or without miR-641 inhibitor (inh-miR-641) detected by qRT-PCR. (C) The protein expression levels of ZEB1 and MDM2 in the SKOV3 and A2780 cells after ciRS-7 knockdown with or without inh-miR-641 detected by Western blot. (D) The expression levels of zeb1 and mdm2 in paired OC (n=40) and adjacent normal tissues (n=40) from 40 patients (same samples as in Figure 1A) detected by qRT-PCR. (E) Pearson correlation analysis of the association between zeb1 or mdm2 with ciRS-7 in the OC tissues (n=40) from 40 OC patients (same samples as in Figure 1A). Relative zeb1 and mdm2 expression levels were calculated by 2^−ΔΔCt method using GAPDH as the internal control. All the experiments were repeated for three times; *P<0.01; **P<0.01