(A) The interrelation between PRNCR1 and miR-126-5p was predicted by starBase. (B,C) Dual-luciferase reporter assay was conducted to identify the impact of miR-126-5p mimic or inhibitor on luciferase intensity controlled by wild-type PRNCR1 or mutant PRNCR1. (D) RIP assay was aimed to examine the PRNCR1 and miR-126-5p enrichment in SPC-A1 and A549 cells. (E) RNA pull-down assay was carried out to analyze the interaction between PRNCR1 and miR-126-5p in NSCLC cells. (F) MiR-126-5p expression was analyzed using qRT-PCR in SPC-A1 and A549 cells. *P<0.05.