Figure 11
(A) Correlation between YIF1B mRNA expression and mutation levels of five significant MMR genes (MLH1, MSH2, MSH6, PMS2, EPCAM). The lower triangle in each tile indicates coefficients calculated by Pearson’s correlation test, and the upper triangle indicates log10 transformed P-value. *: P<0.05, **: P<0.01, ***: P<0.001. (B) Correlation between YIF1B and four methyltransferases (DNMT1: red, DNMT2: blue, DNMT3A: green, DNMT3B: purple) mRNA levels.
Relationship between MMR defects, methyation levels and YIF1B mRNA expression level in various tumors in TCGA database

(A) Correlation between YIF1B mRNA expression and mutation levels of five significant MMR genes (MLH1, MSH2, MSH6, PMS2, EPCAM). The lower triangle in each tile indicates coefficients calculated by Pearson’s correlation test, and the upper triangle indicates log10 transformed P-value. *: P<0.05, **: P<0.01, ***: P<0.001. (B) Correlation between YIF1B and four methyltransferases (DNMT1: red, DNMT2: blue, DNMT3A: green, DNMT3B: purple) mRNA levels.

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