(A,B) A549-RR cells were transfected with miR-219a-5p in combination with or without pcDNA-CD164 and then exposed to 5 Gy irradiation. Apoptosis was evaluated using a TUNEL assay kit. (A) Representative flow analysis images. (B) Statistical results. (C–E) mRNA and protein levels of Bax and Bcl-2 in xenograft tumor in mice were determined using real-time qPCR and Western blot. (F) A549-RR cells were transfected with miR-219a-5p and then exposed to 5 Gy irradiation. Protein expression of γ-H2AX was determined by Western blot. (G) A549-RR cells were transfected with shCD164 and then exposed to 5 Gy irradiation. Protein expression of γ-H2AX was determined by Western blot. (H) A549-RR cells were transfected with miR-219a-5p in combination with or without pcDNA-CD164 and then exposed to 5 Gy irradiation. Protein expression of γ-H2AX was determined by Western blot. (I) Protein expression of γ-H2AX in xenograft tumor in mice was determined by Western blot. *P<0.05.