(A–E) CCK-8 (A,B) and colony formation (C–E) assays showed that interaction among miR-127-5p, TRIM25 and IGF2BP3 played an important role in growth of HepG2 and HepaRG cells. Data are presented as mean ± SD. ***P<0.001 versus NC. ^###P<0.001 versus miR-127-5p mimic. (F–H) Transwell detection showed that interaction among miR-127-5p, TRIM25 and IGF2BP3 played an important role in migration of HepG2 and HepaRG cells. Data are presented as mean ± SD. ***P<0.001 versus NC. ^###P<0.001 versus miR-127-5p mimic. (I–N) qRT-PCR detection showed expression of miR-127-5p, TRIM25 and IGF2BP3. Data are presented as mean ± SD. ***P<0.001 versus NC. ^###P<0.001 versus miR-127-5p mimic.