hsa_circ_0026134 sponges miR-127-5p and regulates TRIM25 and IGF2BP3 expression
(A) Diagrammatic sketch of the binding sites for hsa_circ_0026134 and miR-127-5p. (B) Luciferase reporter assay was conducted to evaluate the interaction ability between hsa_circ_0026134 and miR-127-5p. ***P<0.001. (C) Correlation analysis of miR-127-5p and the 3′ UTR of TRIM25. (D) Luciferase reporter assay was conducted to evaluate the interaction between miR-127-5p and the 3′ UTR of TRIM25. ***P<0.001. (E) Correlation analysis of miR-127-5p and the 3′ UTR of IGF2BP3. (F) Luciferase reporter assay was conducted to evaluate the interaction between miR-127-5p and the 3′ UTR of IGF2BP3. ***P<0.001.