(A) Morphology of tumor xenograft. (B) The change in tumor volume was determined every 7 d during the tumor growth. (C) Tumor weight of nude mice was significantly increased by the transfection with si-RASA1 and reduced when RASA1 overexpressed. (D) The protein expression of RASA1 in each group tumor tissues. (E) The protein expression of Ki-67 in each group tumor tissues. (F) The expression of Ki67 in each group tumor tissues was determined by IHC; *P<0.05, **P<0.01, ***P<0.001.