Figure 5
(A) In 786-0 cells, the expression of miR-223-3p is reduced after up-regulating the expression of RASA1. (B) miR-223-3p mimic and inhibitor transfection efficiency are detected. (C) Up-regulation of miR-223-3p can partially reverse the inhibition of RASA1 on cell proliferation. (D) In ACHN cells, the expression of miR-223-3p is reduced after up-regulating the expression of RASA1. (E) miR-223-3p mimic and inhibitor transfection efficiencies are detected. (F) Up-regulation of miR-223-3p can partially reverse the inhibition of RASA1 on cell proliferation. (G) Up-regulation of miR-223-3p in both cell lines partially reverses the inhibitory effect of RASA1 on cell migration; *P<0.05.
RASA1 functioned by modulating miR-223-3p

(A) In 786-0 cells, the expression of miR-223-3p is reduced after up-regulating the expression of RASA1. (B) miR-223-3p mimic and inhibitor transfection efficiency are detected. (C) Up-regulation of miR-223-3p can partially reverse the inhibition of RASA1 on cell proliferation. (D) In ACHN cells, the expression of miR-223-3p is reduced after up-regulating the expression of RASA1. (E) miR-223-3p mimic and inhibitor transfection efficiencies are detected. (F) Up-regulation of miR-223-3p can partially reverse the inhibition of RASA1 on cell proliferation. (G) Up-regulation of miR-223-3p in both cell lines partially reverses the inhibitory effect of RASA1 on cell migration; *P<0.05.

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