miR-143-3p inhibited the expression of TLR4/MyD88/NF-κB signaling pathway
(A) Sequence of 3′-UTR region in which miR-143-3p bound with MYD88. (B) Dual-luciferase reporter system assay verified the target relationship between miR-143-3p and MYD88. Compared with NC mimic, ΦP<0.05. (C) Expressions of miR-143-3p as well as TLR4, MyD88 and NF-κB p50 mRNA, (D) protein bands of TLR4, MyD88, NF-κB p50 and p-NF-κB p50, (E) protein expressions of TLR4, MyD88, NF-κB p50 and p-NF-κB p50. Compared with normal group, *P<0.05; compared with model group, #P<0.05; compared with NC group, %P<0.05; compared with miR-143-3p mimic group, &P<0.05; compared with miR-143-3p inhibitor group, $P<0.05; compared with TAK-242 group, @P<0.05.