Identification of hub genes in the protein-protein interaction (PPI) networks of upregulated and downregulated significant DEGs
(A) Establishment of PPI network of the up-regulated DEGs using STRING database. (B) The top 10 hub genes in the PPI network of the up-regulated DEGs according to node degree. (C) Establishment of PPI network of the down-regulated DEGs using STRING database. (D) The top 10 hub genes in the PPI network of the down-regulated DEGs according to node degree.