(A) Representative images of TUNEL staining in retinal sections of 6-month-old WT rats and hCRP-Tg rats (Tg). White arrows indicate TUNEL-positive cells (red). Scale bar = 25 μm. (B) Quantification of TUNEL-positive cells. (C) Cell death ELISA was performed in the retina of WT rats and hCRP-Tg rats at the age of 6 months. (D) Representative images of Western blotting for TNF-α, ICAM-1, and CD32 in the retinas of 6 month-old WT rats and hCRP-Tg rats. Each lane represented a single rat. (E) Densitometry quantification of TNF-α, ICAM-1, and CD32 in (D). Data were presented as mean ± SEM (n=8–12). *P<0.05, **P<0.01. Abbreviation: INL, inner nuclear layer.